Could Human Cell Studies Replace Animal Testing?


“At present, animals are used to gauge the toxicity of new chemicals or new chemical combinations before they hit the market, but these tests are expensive and often inaccurate due to the innate difference between laboratory animals and humans,” reported.

In a study published in Nature Communications, lead researchers released the results of the initial Tox21 project in which they tested 10,000 different types of chemical compounds including pesticides, industrial chemicals, food additives and drugs. Each chemical was tested in 15 different concentrations as they reacted with various components of the human cells, according to

Researchers used these tests and generated more than 50 million data points that they could create models with to determine whether this was dangerous to humans or not. This showed that this could be poisonous to both animals and humans, getting rid of the need to test these products on animals, according to

Animal activists have welcomed the research. “To understand more about human development and human diseases, the world’s most forward thinking scientists are developing and implementing methods that supersede the crude use of animals. This welcomes the wealth of advanced non-animal research methodologies that are creating a brighter future for animals and human health,”  Julia Baines, science policy advisor of the organisation People for the Ethical Treatment of Animals (PETA), said, according to